Note: I know this is an old thread, and am just posting to help anyone else who stumbles upon this thread.
WineBottler packages Windows-based programs snugly into OS X app-bundles. No need to install emulators or operating systems - WineBottler uses the great open-source tool Wine to run the binaries on your Mac. There are two choices of know of here. The free WineBottler and the paid-for CrossOver Mac from CodeWeavers. Some commercial software is delivered for OS X this way - I know The Sims 3 game that my wife likes to play on her MacBook Pro is actually the Windows version of the game running under the Wine emulator.
First of all: Wine (just plain wine) is NOT available for Mac, so that leave you with Wineskin, WineBottler, PlayOnMac, or CrossOver.
Wineskin and WineBottler are intended for creating wrappers, which is basically converting it to a Mac application.
Wineskin gives you more customization over your wrapper.
WineBottler also comes with a system that lets you just run any exe on mac just like that.
PlayOnMac lets you download and run supported apps easily, but isn't good for just any exe.
CrossOver is paid software.
Wineskin and WineBottler are intended for creating wrappers, which is basically converting it to a Mac application.
Wineskin gives you more customization over your wrapper.
WineBottler also comes with a system that lets you just run any exe on mac just like that.
PlayOnMac lets you download and run supported apps easily, but isn't good for just any exe.
CrossOver is paid software.
Winebottler For Mac Os X 10.6.8
If all you want to do is run exes with right-click>Open With, than install WineBottler.
